KEGG   REACTION: R03165
Entry
R03165                      Reaction                               
Name
hydroxymethylbilane hydro-lyase(cyclizing)
Definition
Hydroxymethylbilane <=> Uroporphyrinogen III + H2O
Equation
C01024 <=> C01051 + C00001
Reaction class
RC01861  C01024_C01051
Enzyme
4.2.1.75
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Module
M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868  Heme biosynthesis, animals and fungi, glycine => heme
M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75
     R03165  Hydroxymethylbilane <=> Uroporphyrinogen III + H2O
Orthology
K01719  uroporphyrinogen-III synthase [EC:4.2.1.75]
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
K13543  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Other DBs
RHEA: 18968

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (14)   
   KEGG PATHWAY (10)   
   KEGG MODULE (4)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (9932)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (9929)   
All databases (9952)   

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